Science Art Society

Hirosue, S. Facilitating BioCamp as a Japanese living Abroad in BioCamp: Gardens as ‘Biotechnik’ Report (2018) [pdf]

Hirosue, S., D. Kera, H. Huang. Promises and Perils of Open Source Technologies for Development: Can the “Subaltern” Research and Innovate? in Technologies for Development: What is Essential? Hostettler, S., Hazboun, E., Bolay, J.C. Eds. (2015). Springer International Publishing, Switzerland. ISBN: 978-3-319-16246-1

Gaudenz, U., S. Hirosue Lab Making (2014) HLab2014 [pre-print pdf] [on Medium.com]

Hirosue, S., J. Ruxton, L. Salomé, C. Turner, V. Verkeley Eds. [in situ] art • body • medicine: Subtle Technologies 2007. (2007) Coach House Press, Toronto. Subtech07_book

Beesley, P., S. Hirosue, J. Ruxton, M. Tränkle, C. Turner Eds. Responsive Architectures: Subtle Technologies 2006. (2006) Riverside Architectural Press, Cambridge, 2006. ISBN: 978-0978097806 Subtech06 book (amazon)


Academic Science

Wilson DS, Damo M, Hirosue S,Raczy MM, Brünggel K, Diaceri G, Quaglia-Thermes X, Hubbell JA. Synthetically glycosylated antigens induce antigen-specific tolerance and prevent the onset of diabetes. Nature Biomedical Engineering (2019). doi: 10.1038/s41551-019-0424-1

Wilson DS, Hirosue S, Raczy MM, Bonilla-Ramirez L, Jeanbart L, Wang R, Kwissa M, Franetich JF, Broggi MAS, Diaceri G, Quaglia-Thermes X, Mazier D, Swartz MA, Hubbell JA. Antigens reversibly conjugated to a polymeric glyco-adjuvant induce protective humoral and cellular immunity. Nature Materials 18, 175-185 (2019). doi: 10.1038/s41563-018-0256-5


Galan-Navarro C, Rincon-Restrepo M, Zimmer G, Ollmann Saphire E, Hubbell JA, Hirosue S, Swartz MA, Kunz S. Oxidation-sensitive polymersomes as vaccine nanocarriers enhance humoral responses against Lassa virus envelope glycoprotein. Virology 512C (2017) 161-171. doi: 0.1016/j.virol.2017.09.013


Rincon-Restrepo M, Mayer A, Hauert S, Bonner DK, Phelps EA, Hubbell JA, Swartz MA, Hirosue S. (2017) Vaccine nanocarriers: Coupling intracellular pathways and cellular biodistribution to control CD4 vs CD8 T cell responses. Biomaterials, 32:48-58. doi: 10.1016/j.biomaterials.2017.03.047


Dowling DJ, Scott EA, Scheid A, Bergelson I, Joshi S, Pietrasanta C, Brightman S, Sanchez-Schmitz G, Van Haren SD, Ninković J, Kats D, Guiducci C, de Titta A, Bonner DK, Hirosue S, Swartz MA, Hubbell JA, Levy O. (2017) Toll-like receptor 8 agonist nanoparticles mimic immunomodulating effects of the live BCG vaccine and enhance neonatal innate and adaptive immune responses. Journal of Allergy and Clinical Immunology, pii: S0091-6749(17)30242-7. doi: 10.1016/j.jaci.2016.12.985


Cianciaruso, C., Phelps, E. A., Pasquier, M., Hamelin, R., Demurtas, D., Ahmed, M. A., Piemonti, L., Hirosue, S., Swartz, M.A., De Palma, M., Hubbell, J.A., Baekkeskov, S. (2016). Primary Human and Rat Beta Cells Release the Intracellular Autoantigens GAD65, IA-2 and Proinsulin in Exosomes Together with Cytokine-Induced Enhancers of Immunity. Diabetes, db160671. doi: 10.2337/db16-0671


Caucheteux, S. M., Mitchell, J. P., Ivory, M. O., Hirosue, S., Hakobyan, S., Dolton, G.,Ladell, K., Miners, K., Price, D.A., Kan-Mitchell, J., Sewell, A.K., Nestle, F., Moris, A., Karoo, R.O., Birchall, J.C., Swartz, M.A., Hubbell, J.A., Blanchet, F.P. Piguet, V. (2016). Polypropylene Sulfide Nanoparticle p24 Vaccine Promotes Dendritic Cell-Mediated Specific Immune Responses against HIV-1. The Journal of Investigative Dermatology, 136(6), 1172–1181. doi: 10.1016/j.jid.2016.01.033


Hirosue, S., J. Dubrot. Modes of antigen presentation by lymph node stromal cells and their immunological implications. Frontiers in Immunology. (2015). doi: 10.3389/fimmu.2015.00446>


Hirosue, S., E. Vokali, V. Raghavan, M. Rincon-Restrepo, A.W. Lund, F. Capotosti, P. Corthésy-Henrioud, C. Halin Winter, S. Hugues, M.A. Swartz. Steady-state antigen scavenging, cross-presentation and CD8+ T cell priming: a new role for lymphatic endothelial cells. J Immunol. (2014). doi: 10.4049/jimmunol.1302492


Kourtis, I.C., S. Hirosue, A. de Titta, S. Kontos, T. Stengmann, J.A. Hubbell, M.A.Swartz. Peripherally administered nanoparticles target monocytic myeloid cells in blood, secondary lymphoid organs and tumors. PLoS ONE (2013). doi:10.1371/journal.pone.0061646


Swartz, M.A., S. Hirosue, J.A. Hubbell. Engineering approaches to immunotherapy. Science Translational Medicine (2012). doi: 10.1126/scitranslmed.3003763


Lund, A.W., F.V. Duraes, S. Hirosue, V.R. Raghavan, C. Nembrini, S.N. Thomas, A. Issa, S. Hugues, M.A. Swartz. VEGF-C Promotes Immune Tolerance in B16 Melanomas and Cross-Presentation of Tumor Antigen by Lymph Node Lymphatics. Cell Reports 1(3): pp.191-9, (2012). doi: 10.1016/j.celrep.2012.01.005


Eby, J. K., Dane, K. Y., O’neil, C. P., Hirosue, S., Swartz, M. A., & Hubbell, J. A. (2012). Polymer micelles with pyridyl disulfide-coupled antigen travel through lymphatics and show enhanced cellular responses following immunization. Acta Biomaterialia, 8(9), 3210–3217. doi: 10.1016/j.actbio.2012.06.007


Hirosue, S., I.C. Kourtis, J.A. van der Vliés, J.A. Hubbell, M.A. Swartz. Antigen delivery to dendritic cells by poly (propylene sulfide) nanoparticles with disulfide conjugated peptides: Cross-presentation and T cell activation. Vaccine 28(50): pp.7897-7906, (2010). doi: 10.1016/j.vaccine.2010.09.077


Hirosue, S., K. Senn, N. Clément, M. Nonnenmacher, L. Gigout, R.M. Linden, T. Weber. Effect of inhibition of Dynein Function and Microtubule-Altering Drugs on AAV2 Transduction. Virology. 10;367(1):10-8, (2007). doi: 10.1016/j.virol.2007.05.009


Hirosue, S., T. Weber. pH-dependent lytic peptides discovered by phage display. Biochemistry, 45 (20): pp. 6476 -6487, (2006). doi: 10.1021/bi052488s


Hirosue, S., B.G. Müller, R.C. Mulligan, R.S. Langer. Plasmid DNA Encapsulation and Release from Solvent Diffusion Nanospheres. J. Control. Rel. 70: pp. 231-242 , (2001). PMID: 11166423


Dahiyat, B.I., E.M. Posadas, S. Hirosue, E. Hostin, K.W. Leong. Degradable Biomaterials with Elastomeric Characteristics and Drug-carrier Function. React. Polym., 25:2/3, pp.101-109, (1995).


Peeples, T.L., S. Hirosue, G.J. Olson, R.M. Kelly. Coal Sulfur Transformations Monitored by Hyperthermophilic Archaebacteria. Fuel, (1991) 70:5, pp.599-604. doi: 10.1016/0016-2361(91)90173-8


Hirosue, S. moons – self-printed & hand bound, collection of poems, series of 10 (2001) [moons pdf]
On Medium.com as Sachiko Hirosue